Autophagy in bone homeostasis and the onset of osteoporosis.
Ontology highlight
ABSTRACT:
SUBMITTER: Yin X
PROVIDER: S-EPMC6804951 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Autophagy in bone homeostasis and the onset of osteoporosis.
Yin Xing X Zhou Chenchen C Li Jingtao J Liu Renkai R Shi Bing B Yuan Quan Q Zou Shujuan S
Bone research 20191003
Autophagy is an evolutionarily conserved intracellular process, in which domestic cellular components are selectively digested for the recycling of nutrients and energy. This process is indispensable for cell homeostasis maintenance and stress responses. Both genetic and functional studies have demonstrated that multiple proteins involved in autophagic activities are critical to the survival, differentiation, and functioning of bone cells, including osteoblasts, osteocytes, and osteoclasts. Dysr ...[more]
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