Ontology highlight
ABSTRACT:
SUBMITTER: Murano C
PROVIDER: S-EPMC6806250 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Murano Chihiro C Igarashi Akira A Yamauchi Keiko K Inoue Sumito S Watanabe Masafumi M
EXCLI journal 20191007
A 20-year-old woman was diagnosed with stage 4 lung adenocarcinoma with an epidermal growth factor receptor (EGFR) exon 20 insertion gene mutation. Although the patient underwent chemotherapy, her lesions progressed. Liquid biopsy for EGFR T790M mutation showed negative results. After administering osimertinib, reduction of the lesions at the primary site was observed, and the patient's respiratory condition improved. Previous reports showing successful treatment of EGFR exon 20 insertion-positi ...[more]