Dataset Information

Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth.

ABSTRACT: Prior studies have analyzed growth of musculoskeletal tissues between species or across body segments; however, little research has assessed the differences in similar tissues within a single joint. Here we studied changes in the length and cross-sectional area of four ligaments and tendons, (anterior cruciate ligament, patellar tendon, medial collateral ligament, lateral collateral ligament) in the tibiofemoral joint of female Yorkshire pigs through high-field magnetic resonance imaging throughout growth. Tissue lengths increased by 4- to 5-fold from birth to late adolescence across the tissues while tissue cross-sectional area increased by 10-20-fold. The anterior cruciate ligament and lateral collateral ligament showed allometric growth favoring change in length over change in cross-sectional area while the patellar tendon and medial collateral ligament grow in an isometric manner. Additionally, changes in the length and cross-sectional area of the anterior cruciate ligament did not increase as much as in the other ligaments and tendon of interest. Overall, these findings suggest that musculoskeletal soft tissue morphometry can vary within tissues of similar structure and within a single joint during post-natal growth.

SUBMITTER: Cone SG

PROVIDER: S-EPMC6808441 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth.

Cone Stephanie G SG Piercy Hope E HE Lambeth Emily P EP Ru Hongyu H Piedrahita Jorge A JA Spang Jeffrey T JT Fordham Lynn A LA Fisher Matthew B MB

PloS one 20191023 10

Prior studies have analyzed growth of musculoskeletal tissues between species or across body segments; however, little research has assessed the differences in similar tissues within a single joint. Here we studied changes in the length and cross-sectional area of four ligaments and tendons, (anterior cruciate ligament, patellar tendon, medial collateral ligament, lateral collateral ligament) in the tibiofemoral joint of female Yorkshire pigs through high-field magnetic resonance imaging through ...[more]

PMID: 31644571

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Dataset Information

Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth.

Publications

Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth.

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