Ontology highlight
ABSTRACT:
SUBMITTER: Kaur R
PROVIDER: S-EPMC6810332 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Kaur Rashmit R Surala Michael M Hoger Sebastian S Grössmann Nicole N Grimm Alexandra A Timaeus Lorin L Kallina Wolfgang W Hummel Thomas T
Science advances 20191023 10
Interhemispheric synaptic connections, a prominent feature in animal nervous systems for the rapid exchange and integration of neuronal information, can appear quite suddenly during brain evolution, raising the question about the underlying developmental mechanism. Here, we show in the Drosophila olfactory system that the induction of a bilateral sensory map, an evolutionary novelty in dipteran flies, is mediated by a unique type of commissural pioneer interneurons (cPINs) via the localized acti ...[more]