Ontology highlight
ABSTRACT:
SUBMITTER: Son YE
PROVIDER: S-EPMC6811503 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Son Ye-Eun YE Fu Ci C Jung Won-Hee WH Oh Sang-Hun SH Kwak Jin-Hwan JH Cardenas Maria E ME Heitman Joseph J Park Hee-Soo HS
Frontiers in cellular and infection microbiology 20191017
The Mkt1-Pbp1 complex promotes mating-type switching by regulating the translation of <i>HO</i> mRNA in <i>Saccharomyces cerevisiae</i>. Here, we performed <i>in vivo</i> immunoprecipitation assays and mass spectrometry analyses in the human fungal pathogen <i>Cryptococcus neoformans</i> to show that Pbp1, a poly(A)-binding protein-binding protein, interacts with Mkt1 containing a PIN like-domain. Association of Pbp1 with Mkt1 was confirmed by co-immunoprecipitation assays. Results of spot dilut ...[more]