Ontology highlight
ABSTRACT:
SUBMITTER: Omlor W
PROVIDER: S-EPMC6811620 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Nature communications 20191023 1
Neuronal networks of the mammalian motor cortex (M1) are important for dexterous control of limb joints. Yet it remains unclear how encoding of joint movement in M1 depends on varying environmental contexts. Using calcium imaging we measured neuronal activity in layer 2/3 of the M1 forelimb region while mice grasped regularly or irregularly spaced ladder rungs during locomotion. We found that population coding of forelimb joint movements is sparse and varies according to the flexibility demanded ...[more]