Antigen array for serological diagnosis and novel allergen identification in severe equine asthma.
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ABSTRACT:
SUBMITTER: White SJ
PROVIDER: S-EPMC6811683 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
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Antigen array for serological diagnosis and novel allergen identification in severe equine asthma.
White S J SJ Moore-Colyer M M Marti E E Hannant D D Gerber V V Coüetil L L Richard E A EA Alcocer M M
Scientific reports 20191023 1
Severe equine asthma (sEA), which closely resembles human asthma, is a debilitating and performance-limiting allergic respiratory disorder which affects 14% of horses in the Northern Hemisphere and is associated with increased allergen-specific immunoglobulin E (IgE) against a range of environmental proteins. A comprehensive microarray platform was developed to enable the simultaneous detection of allergen-specific equine IgE in serum against a wide range of putative allergenic proteins. The mic ...[more]
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