Ontology highlight
ABSTRACT:
SUBMITTER: Pyle JR
PROVIDER: S-EPMC6813813 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Pyle Joseph R JR Sy Piecco Kurt Waldo E KWE Vicente Juvinch R JR Chen Jixin J
Langmuir : the ACS journal of surfaces and colloids 20190820 35
Reactive oxygen species (ROS) are a necessary evil in many biological systems and have been measured with fluorescent probes at the ensemble levels both in vitro and in vivo. Measuring ROS generated from a single molecule is important for mechanistic studies, yet measuring ROS near a dye-labeled single-molecule under illumination has been challenging. Here, we use CellROX, a group of ROS probes, to sense ROS near dye-stained DNA that has been flow-stretched and immobilized on a surface. ROS is r ...[more]