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Virus structures constrain transmission modes.


ABSTRACT: Here we investigate links between the structures of viruses and routes of transmission. Viruses show a wide range of different structures, and the transmission of viruses between vertebrate hosts can take place through many different routes. We compiled a database of 243 virus-host combinations and report a statistical analysis that documents the associations between structures and routes of transmission-for example, viruses that are transmitted by the faecal-oral mode of infection are rarely enclosed in a lipid envelope.

SUBMITTER: Bushman FD 

PROVIDER: S-EPMC6814542 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Virus structures constrain transmission modes.

Bushman Frederic D FD   McCormick Kevin K   Sherrill-Mix Scott S  

Nature microbiology 20190729 11


Here we investigate links between the structures of viruses and routes of transmission. Viruses show a wide range of different structures, and the transmission of viruses between vertebrate hosts can take place through many different routes. We compiled a database of 243 virus-host combinations and report a statistical analysis that documents the associations between structures and routes of transmission-for example, viruses that are transmitted by the faecal-oral mode of infection are rarely en  ...[more]

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