Ontology highlight
ABSTRACT:
SUBMITTER: Melani RD
PROVIDER: S-EPMC6816405 | biostudies-literature | 2019 Nov-Dec
REPOSITORIES: biostudies-literature
Melani Rafael D RD Srzentić Kristina K Gerbasi Vincent R VR McGee John P JP Huguet Romain R Fornelli Luca L Kelleher Neil L NL
mAbs 20191013 8
The analysis of monoclonal antibodies (mAbs) by a middle-down mass spectrometry (MS) approach is a growing field that attracts the attention of many researchers and biopharmaceutical companies. Usually, liquid fractionation techniques are used to separate mAbs polypeptides chains before MS analysis. Gas-phase fractionation techniques such as high-field asymmetric waveform ion mobility spectrometry (FAIMS) can replace liquid-based separations and reduce both analysis time and cost. Here, we prese ...[more]