Association of ADIPOQ, leptin, LEPR, and resistin polymorphisms with obesity parameters in Hammam Sousse Sahloul Heart Study.
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ABSTRACT:
SUBMITTER: Zayani N
PROVIDER: S-EPMC6817023 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
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Association of ADIPOQ, leptin, LEPR, and resistin polymorphisms with obesity parameters in Hammam Sousse Sahloul Heart Study.
Zayani Nesrine N Omezzine Asma A Boumaiza Imen I Achour Ons O Rebhi Lamia L Rejeb Jihen J Ben Rejeb Nabila N Ben Abdelaziz Ahmed A Bouslama Ali A
Journal of clinical laboratory analysis 20170213 6
<h4>Background</h4>Adipose tissue is an important endocrine organ that secretes a number of adipokines, such as adiponectin (ADIPOQ), leptin (LEP), leptin receptor (LEPR), and resistin (RETN) which may be implicated in obesity. Some adipokines' polymorphisms of genes might influence their concentrations and/or activities. Our aim was to study the relationship between seven SNPs in ADIPOQ (+45T<G (rs2241766); +276G<T (rs1501299); -4255C<T (rs822393); -395G<T (rs17366568)), LEP (2548G<A (rs7799039 ...[more]
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