Relationship between serum cytokines receptors and matrix metalloproteinase 9 levels and coronary artery disease.

ABSTRACT: The prevalence of coronary artery disease (CAD) is increasing globally, supporting the need for the identification of novel biomarkers. Therefore in the present study, we have explored the association of SIL2A, SIL6R, STNFRI, STNFRII, and MMP9 in CAD patients. Twenty one patients with angiographically defined CAD with more than 50% occlusion, at least, in one coronary artery and twenty healthy subjects (n=20) without the history of cardiovascular symptoms were enrolled. Demographic and biochemical analysis (e.g. Total Cholesterol (TC), Triglyceride (TG), and HDL-C) were measured in all the subjects. The level of cytokines receptor (SIL2A, SIL6R, SIL6R, STNFRI, STNFRII, and matrix metallopeptidase 9 (MMP9) were evaluated. Our results showed the higher level of MMP9 in patients group compare

SUBMITTER: Mirhafez SR 

PROVIDER: S-EPMC6817073 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature