Dataset Information

Influence of talker discontinuity on cortical dynamics of auditory spatial attention.

ABSTRACT: In everyday acoustic scenes, listeners face the challenge of selectively attending to a sound source and maintaining attention on that source long enough to extract meaning. This task is made more daunting by frequent perceptual discontinuities in the acoustic scene: talkers move in space and conversations switch from one speaker to another in a background of many other sources. The inherent dynamics of such switches directly impact our ability to sustain attention. Here we asked how discontinuity in talker voice affects the ability to focus auditory attention to sounds from a particular location as well as neural correlates of underlying processes. During electroencephalography recordings, listeners attended to a stream of spoken syllables from one direction while ignoring distracting syllables from a different talker from the opposite hemifield. On some trials, the talker switched locations in the middle of the streams, creating a discontinuity. This switch disrupted attentional modulation of cortical responses; specifically, event-related potentials evoked by syllables in the to-be-attended direction were suppressed and power in alpha oscillations (8-12?Hz) were reduced following the discontinuity. Importantly, at an individual level, the ability to maintain attention to a target stream and report its content, despite the discontinuity, correlates with the magnitude of the disruption of these cortical responses. These results have implications for understanding cortical mechanisms supporting attention. The changes in the cortical responses may serve as a predictor of how well individuals can communicate in complex acoustic scenes and may help in the development of assistive devices and interventions to aid clinical populations.

SUBMITTER: Mehraei G

PROVIDER: S-EPMC6817367 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Influence of talker discontinuity on cortical dynamics of auditory spatial attention.

Mehraei Golbarg G Shinn-Cunningham Barbara B Dau Torsten T

NeuroImage 20180628

In everyday acoustic scenes, listeners face the challenge of selectively attending to a sound source and maintaining attention on that source long enough to extract meaning. This task is made more daunting by frequent perceptual discontinuities in the acoustic scene: talkers move in space and conversations switch from one speaker to another in a background of many other sources. The inherent dynamics of such switches directly impact our ability to sustain attention. Here we asked how discontinui ...[more]

PMID: 29960089

Similar Datasets

Project description:This combined fMRI and MEG study investigated brain activations during listening and attending to natural auditory scenes. We first recorded, using in-ear microphones, vocal non-speech sounds, and environmental sounds that were mixed to construct auditory scenes containing two concurrent sound streams. During the brain measurements, subjects attended to one of the streams while spatial acoustic information of the scene was either preserved (stereophonic sounds) or removed (monophonic sounds). Compared to monophonic sounds, stereophonic sounds evoked larger blood-oxygenation-level-dependent (BOLD) fMRI responses in the bilateral posterior superior temporal areas, independent of which stimulus attribute the subject was attending to. This finding is consistent with the functional role of these regions in the (automatic) processing of auditory spatial cues. Additionally, significant differences in the cortical activation patterns depending on the target of attention were observed. Bilateral planum temporale and inferior frontal gyrus were preferentially activated when attending to stereophonic environmental sounds, whereas when subjects attended to stereophonic voice sounds, the BOLD responses were larger at the bilateral middle superior temporal gyrus and sulcus, previously reported to show voice sensitivity. In contrast, the time-resolved MEG responses were stronger for mono- than stereophonic sounds in the bilateral auditory cortices at ~360 ms after the stimulus onset when attending to the voice excerpts within the combined sounds. The observed effects suggest that during the segregation of auditory objects from the auditory background, spatial sound cues together with other relevant temporal and spectral cues are processed in an attention-dependent manner at the cortical locations generally involved in sound recognition. More synchronous neuronal activation during monophonic than stereophonic sound processing, as well as (local) neuronal inhibitory mechanisms in the auditory cortex, may explain the simultaneous increase of BOLD responses and decrease of MEG responses. These findings highlight the complimentary role of electrophysiological and hemodynamic measures in addressing brain processing of complex stimuli.

Project description:To navigate complex acoustic environments, listeners adapt neural processes to focus on behaviorally relevant sounds in the acoustic foreground while minimizing the impact of distractors in the background, an ability referred to as top-down selective attention. Particularly striking examples of attention-driven plasticity have been reported in primary auditory cortex via dynamic reshaping of spectro-temporal receptive fields (STRFs). By enhancing the neural response to features of the foreground while suppressing those to the background, STRFs can act as adaptive contrast matched filters that directly contribute to an improved cognitive segregation between behaviorally relevant and irrelevant sounds. In this study, we propose a novel discriminative framework for modeling attention-driven plasticity of STRFs in primary auditory cortex. The model describes a general strategy for cortical plasticity via an optimization that maximizes discriminability between the foreground and distractors while maintaining a degree of stability in the cortical representation. The first instantiation of the model describes a form of feature-based attention and yields STRF adaptation patterns consistent with a contrast matched filter previously reported in neurophysiological studies. An extension of the model captures a form of object-based attention, where top-down signals act on an abstracted representation of the sensory input characterized in the modulation domain. The object-based model makes explicit predictions in line with limited neurophysiological data currently available but can be readily evaluated experimentally. Finally, we draw parallels between the model and anatomical circuits reported to be engaged during active attention. The proposed model strongly suggests an interpretation of attention-driven plasticity as a discriminative adaptation operating at the level of sensory cortex, in line with similar strategies previously described across different sensory modalities.

Project description:Audiovisual cross-modal training has been proposed as a tool to improve human spatial hearing. Here, we investigated training-induced modulations of event-related potential (ERP) components that have been associated with processes of auditory selective spatial attention when a speaker of interest has to be localized in a multiple speaker ("cocktail-party") scenario. Forty-five healthy participants were tested, including younger (19-29 years; n = 21) and older (66-76 years; n = 24) age groups. Three conditions of short-term training (duration 15 min) were compared, requiring localization of non-speech targets under "cocktail-party" conditions with either (1) synchronous presentation of co-localized auditory-target and visual stimuli (audiovisual-congruency training) or (2) immediate visual feedback on correct or incorrect localization responses (visual-feedback training), or (3) presentation of spatially incongruent auditory-target and visual stimuli presented at random positions with synchronous onset (control condition). Prior to and after training, participants were tested in an auditory spatial attention task (15 min), requiring localization of a predefined spoken word out of three distractor words, which were presented with synchronous stimulus onset from different positions. Peaks of ERP components were analyzed with a specific focus on the N2, which is known to be a correlate of auditory selective spatial attention. N2 amplitudes were significantly larger after audiovisual-congruency training compared with the remaining training conditions for younger, but not older, participants. Also, at the time of the N2, distributed source analysis revealed an enhancement of neural activity induced by audiovisual-congruency training in dorsolateral prefrontal cortex (Brodmann area 9) for the younger group. These findings suggest that cross-modal processes induced by audiovisual-congruency training under "cocktail-party" conditions at a short time scale resulted in an enhancement of correlates of auditory selective spatial attention.

Dataset Information

Influence of talker discontinuity on cortical dynamics of auditory spatial attention.

Publications

Influence of talker discontinuity on cortical dynamics of auditory spatial attention.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets