What Kind of Brain Structural Connectivity Remodeling Can Relate to Residual Motor Function After Stroke?

ABSTRACT: Recent findings showed that brain networks far away from a lesion could be altered to adapt changes after stroke. This study examined 13 chronic stroke patients with moderate to severe motor impairment and 13 age-comparable healthy controls using diffusion tensor imaging to investigate the stroke impact on the reorganization of structural connectivity. Each subject's brain was segmented into 68 cortical and 12 subcortical regions of interest (ROIs), and connectivity measures including fractional anisotropy (FA), regional FA (rFA), connection weight (CW) and connection strength (CS) were adopted to compare two subject groups. Correlations between these measures and clinical scores of motor functions (Action Research Arm Test and Fugl-Meyer Assessment for upper extremity) were done. Network-

SUBMITTER: Wong WW 

PROVIDER: S-EPMC6819511 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature