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Antibiotics prescription and guidelines adherence in elderly: impact of the comorbidities.


ABSTRACT:

Background

Although the interest of antibiotics is well known, antibiotics prescription is associated with side effect, especially in patients with multiples comorbidities. One way to reduce the incidence of side effects is to respect antibiotics prescriptions guidelines. Our objective was to investigated the factors associated with guidelines adherence in elderly patients with multiples comorbidities.

Methods

From October 2015 to December 2016, antibiotics prescription and guidelines adherence were analyzed in two post-acute care and rehabilitation services of a 2600-bed, university-affiliated center.

Results

One hundred and twenty-eight patients were included, fifty-nine (46%) patients had antibiotics prescription according to guidelines. In Multivariable logistic regression analysis, prescription of 2 antibiotics or more (OR?=?0.168, 95% IC?=?0.037-0.758, p?ConclusionsHigh comorbidity in the elderly was negatively associated with the guidelines adherence of antibioti?s prescriptions. These criteria should be considered to optimize antibiotics prescriptions in elderly patients.

SUBMITTER: Dylis A 

PROVIDER: S-EPMC6819552 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Publications

Antibiotics prescription and guidelines adherence in elderly: impact of the comorbidities.

Dylis Anthony A   Boureau Anne Sophie AS   Coutant Audrey A   Batard Eric E   Javaudin François F   Berrut Gilles G   de Decker Laure L   Chapelet Guillaume G  

BMC geriatrics 20191029 1


<h4>Background</h4>Although the interest of antibiotics is well known, antibiotics prescription is associated with side effect, especially in patients with multiples comorbidities. One way to reduce the incidence of side effects is to respect antibiotics prescriptions guidelines. Our objective was to investigated the factors associated with guidelines adherence in elderly patients with multiples comorbidities.<h4>Methods</h4>From October 2015 to December 2016, antibiotics prescription and guidel  ...[more]

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