Dataset Information

Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: A qualitative study.

ABSTRACT:

Introduction

Resectional surgery remains the mainstay of treatment for colorectal cancer. A heightened postoperative systemic inflammatory response has been shown to correlate negatively with short/long-term outcomes. Perioperative steroid administration may help to alleviate this systemic inflammatory response. This survey has been carried out to assess current attitudes towards perioperative steroid use and to gauge interest in a randomised control trial in this area.

Method

An internet-based survey consisting of 9 questions was circulated via email. Those responses from outside the United Kingdom were excluded.

Result

74 doctors from the United Kingdom, predominantly Consultant Anaesthetists (54%) responded to this survey. 77% gave some or all of their patients steroids, in 75% of cases at the discretion of the anaesthetist. The main perceived benefit was to reduce postoperative nausea and vomiting. Diabetics and those deemed at high risk of wound infection were the group in whom most respondents would be reluctant to give steroids. 32% of respondents had no concerns. 87% of respondents felt that a randomised trial in this field would be of clinical interest with most respondents (58%) preferring a three-armed trial - no steroids vs low dose steroids vs high dose steroids.

Conclusion

This survey indicated that perioperative steroid use is currently widespread. Sufficient equipoise exists for a trial in this area with regard to examining the impact of dexamethasone on postoperative complications and the postoperative systemic inflammatory response. Respondents favoured a 3-armed trial - no steroids vs low-dose steroids vs high-dose steroids.

SUBMITTER: Golder AM

PROVIDER: S-EPMC6820077 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Publications

Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: A qualitative study.

Golder Allan M AM McSorley Stephen T ST Kearns Rachel J RJ McMillan Donald C DC Horgan Paul G PG Roxburgh Campbell S CS

Annals of medicine and surgery (2012) 20191011

<h4>Introduction</h4>Resectional surgery remains the mainstay of treatment for colorectal cancer. A heightened postoperative systemic inflammatory response has been shown to correlate negatively with short/long-term outcomes. Perioperative steroid administration may help to alleviate this systemic inflammatory response. This survey has been carried out to assess current attitudes towards perioperative steroid use and to gauge interest in a randomised control trial in this area.<h4>Method</h4>An ...[more]

PMID: 31687135

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Dataset Information

Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: A qualitative study.

Introduction

Method

Result

Conclusion

Publications

Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: A qualitative study.

Similar Datasets

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