Ontology highlight
ABSTRACT:
SUBMITTER: Madaro L
PROVIDER: S-EPMC6821135 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Madaro Luca L Torcinaro Alessio A De Bardi Marco M Contino Federica F FF Pelizzola Mattia M Diaferia Giuseppe R GR Imeneo Giulia G Bouchè Marina M Puri Pier Lorenzo PL De Santa Francesca F
PLoS genetics 20191018 10
Satellite cells (SCs) are muscle stem cells that remain quiescent during homeostasis and are activated in response to acute muscle damage or in chronic degenerative conditions such as Duchenne Muscular Dystrophy. The activity of SCs is supported by specialized cells which either reside in the muscle or are recruited in regenerating skeletal muscles, such as for instance macrophages (MΦs). By using a dystrophic mouse model of transient MΦ depletion, we describe a shift in identity of muscle stem ...[more]