Ontology highlight
ABSTRACT:
SUBMITTER: Movahed S
PROVIDER: S-EPMC6821566 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Movahed Saeid S Azad Zubair Z Dangi Saroj S Riehn Robert R
Nanotechnology 20190713 41
Nanofluidic devices have channel dimensions which come to within one order of magnitude of the Debye length of common aqueous solutions. Conventionally, external driving is used to create concentration polarization of ions and biomolecules in nanofluidic devices. Here we show that long-range ionic strength gradients intrinsic to all nanofluidic devices, even at equilibrium, also drive a drift of macromolecules. To demonstrate the effect, we confine long DNA to straight nanochannels of constant, ...[more]