Ontology highlight
ABSTRACT:
SUBMITTER: Kobb AB
PROVIDER: S-EPMC6822589 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Kobb Anna B AB Rothenberg Katheryn E KE Fernandez-Gonzalez Rodrigo R
Molecular biology of the cell 20190925 23
Collective cell movements play a central role in embryonic development, tissue repair, and metastatic disease. Cell movements are often coordinated by supracellular networks formed by the cytoskeletal protein actin and the molecular motor nonmuscle myosin II. During wound closure in the embryonic epidermis, the cells around the wound migrate collectively into the damaged region. In <i>Drosophila</i> embryos, mechanical tension stabilizes myosin at the wound edge, facilitating the assembly of a s ...[more]