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Objective and Subjective Effects of a Prototype Nasal Dilator Strip on Sleep in Subjects with Chronic Nocturnal Nasal Congestion.

ABSTRACT: INTRODUCTION:This exploratory study characterized the performance of a nasal dilator strip with improved spring forces in lowering nasal resistance during sleep and reducing sleep-disordered breathing in subjects with difficulty sleeping due to chronic nocturnal nasal congestion. METHODS:Subjects applied the strip at bedtime for 28 days (active phase; n?=?70). Objective assessments included snoring variables, breathing route during sleep, and polysomnography measures compared with baseline. Nasal breathing, congestion, and sleep were measured subjectively using rating scales and questionnaires. During a crossover nasal resistance phase (n?=?55), nasal resistance was measured using posterior rhinomanometry with the strip applied on one of two nights. RESULTS:In the active phase, breathing and sleep were perceived to improve, with less daytime sleepiness (P?

SUBMITTER: Wheatley JR

PROVIDER: S-EPMC6822853 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Objective and Subjective Effects of a Prototype Nasal Dilator Strip on Sleep in Subjects with Chronic Nocturnal Nasal Congestion.

Wheatley John R JR Amis Terence C TC Lee Sharon A SA Ciesla Renee R Shanga Gilbert G

Advances in therapy 20190522 7

<h4>Introduction</h4>This exploratory study characterized the performance of a nasal dilator strip with improved spring forces in lowering nasal resistance during sleep and reducing sleep-disordered breathing in subjects with difficulty sleeping due to chronic nocturnal nasal congestion.<h4>Methods</h4>Subjects applied the strip at bedtime for 28 days (active phase; n = 70). Objective assessments included snoring variables, breathing route during sleep, and polysomnography measures compared with ...[more]

PMID: 31119695

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