Ontology highlight
ABSTRACT:
SUBMITTER: Bull JJ
PROVIDER: S-EPMC6824332 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Bull James J JJ Remien Christopher H CH Gomulkiewicz Richard R Krone Stephen M SM
PeerJ 20191029
Gene drives may be used in two ways to curtail vectored diseases. Both involve engineering the drive to spread in the vector population. One approach uses the drive to directly depress vector numbers, possibly to extinction. The other approach leaves intact the vector population but suppresses the disease agent during its interaction with the vector. This second application may use a drive engineered to carry a genetic cargo that blocks the disease agent. An advantage of the second application i ...[more]