Ontology highlight
ABSTRACT:
SUBMITTER: Gaertner B
PROVIDER: S-EPMC6824472 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Genes & development 20191101 21-22
A comprehensive understanding of mechanisms that underlie the development and function of human cells requires human cell models. For the pancreatic lineage, protocols have been developed to differentiate human pluripotent stem cells (hPSCs) into pancreatic endocrine and exocrine cells through intermediates resembling in vivo development. In recent years, this differentiation system has been employed to decipher mechanisms of pancreatic development, congenital defects of the pancreas, as well as ...[more]