Localized compliance measurement of the airway wall using anatomic optical coherence elastography.
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ABSTRACT:
SUBMITTER: Bu R
PROVIDER: S-EPMC6825607 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Localized compliance measurement of the airway wall using anatomic optical coherence elastography.
Bu Ruofei R Balakrishnan Santosh S Price Hillel H Zdanski Carlton C Mitran Sorin S Oldenburg Amy L AL
Optics express 20190601 12
We describe an elastographic method to circumferentially-resolve airway wall compliance using endoscopic, anatomic optical coherence tomography (aOCT) combined with an intraluminal pressure catheter. The method was first demonstrated on notched silicone phantoms of known elastic modulus under respiratory ventilation, where localized compliance measurements were validated against those predicted by finite element modeling. Then, ex vivo porcine tracheas were scanned, and the pattern of compliance ...[more]
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