Ontology highlight
ABSTRACT:
SUBMITTER: Gant TW
PROVIDER: S-EPMC6826341 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Gant Timothy W TW Sauer Ursula G UG Zhang Shu-Dong SD Chorley Brian N BN Hackermüller Jörg J Perdichizzi Stefania S Tollefsen Knut E KE van Ravenzwaay Ben B Yauk Carole C Tong Weida W Poole Alan A
Regulatory toxicology and pharmacology : RTP 20171104
A generic Transcriptomics Reporting Framework (TRF) is presented that lists parameters that should be reported in 'omics studies used in a regulatory context. The TRF encompasses the processes from transcriptome profiling from data generation to a processed list of differentially expressed genes (DEGs) ready for interpretation. Included within the TRF is a reference baseline analysis (RBA) that encompasses raw data selection; data normalisation; recognition of outliers; and statistical analysis. ...[more]