PTEN and Gynecological Cancers.
Ontology highlight
ABSTRACT:
SUBMITTER: Nero C
PROVIDER: S-EPMC6826459 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
PTEN and Gynecological Cancers.
Nero Camilla C Ciccarone Francesca F Pietragalla Antonella A Scambia Giovanni G
Cancers 20190928 10
PTEN is a tumour suppressor gene, and its loss of function is frequently observed in both heritable and sporadic cancers. It is involved in a great variety of biological processes, including maintenance of genomic stability, cell survival, migration, proliferation and metabolism. A better understanding of PTEN activity and regulation has therefore emerged as a subject of primary interest in cancer research. Gynaecological cancers are variously interested by PTEN deregulation and many perspective ...[more]
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