Ontology highlight
ABSTRACT:
SUBMITTER: Bazarbachi AH
PROVIDER: S-EPMC6826920 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Bazarbachi Abdul Hamid AH Al Hamed Rama R Malard Florent F Mohty Mohamad M Bazarbachi Ali A
Therapeutic advances in hematology 20191101
FMS-like tyrosine kinase 3 (<i>FLT3</i>) mutations are one of the most frequently encountered genetic alterations in acute myeloid leukemia (AML), and are generally associated with unfavorable outcomes. Several tools are currently available to provide an accurate prognosis for patients with these mutations, including <i>FLT3</i> mutation type (internal tandem duplication <i>versus</i> tyrosine kinase domain), mutation allelic ratio (high <i>versus</i> low), and concurrent nucleophosmin-1 (<i>NPM ...[more]