Ontology highlight
ABSTRACT:
SUBMITTER: Viborg AH
PROVIDER: S-EPMC6827312 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Viborg Alexander Holm AH Terrapon Nicolas N Lombard Vincent V Michel Gurvan G Czjzek Mirjam M Henrissat Bernard B Brumer Harry H
The Journal of biological chemistry 20190909 44
Glycoside hydrolase family (GH) 16 comprises a large and taxonomically diverse family of glycosidases and transglycosidases that adopt a common β-jelly-roll fold and are active on a range of terrestrial and marine polysaccharides. Presently, broadly insightful sequence-function correlations in GH16 are hindered by a lack of a systematic subfamily structure. To fill this gap, we have used a highly scalable protein sequence similarity network analysis to delineate nearly 23,000 GH16 sequences into ...[more]