Ontology highlight
ABSTRACT:
SUBMITTER: Benner L
PROVIDER: S-EPMC6827387 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Benner Leif L Castro Elias A EA Whitworth Cale C Venken Koen J T KJT Yang Haiwang H Fang Junnan J Oliver Brian B Cook Kevin R KR Lerit Dorothy A DA
Genetics 20190926 3
Heterochromatin-mediated repression is essential for controlling the expression of transposons and for coordinated cell type-specific gene regulation. The <i>small ovary</i> (<i>sov</i>) locus was identified in a screen for female-sterile mutations in <i>Drosophila melanogaster</i>, and mutants show dramatic ovarian morphogenesis defects. We show that the null <i>sov</i> phenotype is lethal and map the locus to the uncharacterized gene <i>CG14438</i>, which encodes a nuclear zinc-finger protein ...[more]