Unknown

Dataset Information

0

Optoacoustic imaging of the breast: correlation with histopathology and histopathologic biomarkers.


ABSTRACT: AIM:This study was conducted in order to investigate the role of gray-scale ultrasound (US) and optoacoustic imaging combined with gray-scale ultrasound (OA/US) to better differentiate between breast cancer molecular subtypes. MATERIALS AND METHODS:All 67 malignant masses included in the Maestro trial were retrospectively reviewed to compare US and OA/US feature scores and histopathological findings. Kruskal-Wallis tests were used to analyze the relationship between US and OA/US features and molecular subtypes of breast cancer. If a significant relationship was found, additional Wilcoxon-Mann-Whitney tests were used to identify the differences between molecular subtype groups. RESULTS:US sound transmission helped to differentiate between LUMA and LUMB, LUMB and TNBC, and LUMB and all other molecular subtypes combined (p values?

SUBMITTER: Menezes GLG 

PROVIDER: S-EPMC6828639 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Optoacoustic imaging of the breast: correlation with histopathology and histopathologic biomarkers.

Menezes Gisela L G GLG   Mann Ritse M RM   Meeuwis Carla C   Bisschops Bob B   Veltman Jeroen J   Lavin Philip T PT   van de Vijver Marc J MJ   Pijnappel Ruud M RM  

European radiology 20190527 12


<h4>Aim</h4>This study was conducted in order to investigate the role of gray-scale ultrasound (US) and optoacoustic imaging combined with gray-scale ultrasound (OA/US) to better differentiate between breast cancer molecular subtypes.<h4>Materials and methods</h4>All 67 malignant masses included in the Maestro trial were retrospectively reviewed to compare US and OA/US feature scores and histopathological findings. Kruskal-Wallis tests were used to analyze the relationship between US and OA/US f  ...[more]

Similar Datasets

| S-EPMC6149278 | biostudies-literature
| S-EPMC4017075 | biostudies-literature
| S-EPMC5496681 | biostudies-literature
| S-EPMC7977664 | biostudies-literature
| S-EPMC6692775 | biostudies-literature
| S-EPMC6403272 | biostudies-literature
| S-EPMC3504320 | biostudies-other
| S-EPMC3551502 | biostudies-literature
| S-EPMC8145174 | biostudies-literature
| S-EPMC2843833 | biostudies-other