Effect of population stratification on SNP-by-environment interaction.
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ABSTRACT:
SUBMITTER: An J
PROVIDER: S-EPMC6829023 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Effect of population stratification on SNP-by-environment interaction.
An Jaehoon J Won Sungho S Lutz Sharon M SM Hecker Julian J Lange Christoph C
Genetic epidemiology 20190820 8
Proportions of false-positive rates in genome-wide association analysis are affected by population stratification, and if it is not correctly adjusted, the statistical analysis can produce the large false-negative finding. Therefore various approaches have been proposed to adjust such problems in genome-wide association studies. However, in spite of its importance, a few studies have been conducted in genome-wide single nucleotide polymorphism (SNP)-by-environment interaction studies. In this re ...[more]
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