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Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre.


ABSTRACT: Gymnema sylvestre is a plant included in Apocynaceae family and is located in many regions of Asia, Africa and Australia. This plant is widely used as a traditional therapy for different purposes. Even now it is being used as a dietary supplement due to its numerous therapeutic uses. It is known to have blood glucose lowering potential and, thus, is widely used in traditional and Ayurvedic systems of medicine. It renders glucose lowering activity due to the presence of phytochemicals, such as gurmarin, gymnemic acid as well as gymnemasaponins. Gymnema sylvestre is also known to have anti-oxidant, antibiotic, anti-inflammatory, antiviral, gastro and hepatoprotective, anticancer and lipid-lowering activities. This review discusses in details on different pharmacological and clinical potentials of Gymnema sylvestre and its chemical constituents associated with its therapeutic potentials.

SUBMITTER: Khan F 

PROVIDER: S-EPMC6830388 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of <i>Gymnema sylvestre</i>.

Khan Farzana F   Sarker Md Moklesur Rahman MMR   Ming Long Chiau LC   Mohamed Isa Naina IN   Zhao Chao C   Sheikh Bassem Y BY   Tsong Hiew Fei HF   Rashid Mohammad A MA  

Frontiers in pharmacology 20191029


<i>Gymnema sylvestre</i> is a plant included in Apocynaceae family and is located in many regions of Asia, Africa and Australia. This plant is widely used as a traditional therapy for different purposes. Even now it is being used as a dietary supplement due to its numerous therapeutic uses. It is known to have blood glucose lowering potential and, thus, is widely used in traditional and Ayurvedic systems of medicine. It renders glucose lowering activity due to the presence of phytochemicals, suc  ...[more]

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