Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC6831607 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Zhang Longbo L Liu Zhiqiang Z Li Jin J Huang Tianxiang T Wang Ying Y Chang Lianpeng L Zheng Wenjie W Ma Yujie Y Chen Fenghua F Gong Xuan X Yuan Qianying Q Teaw Shannon S Fang Xinqi X Song Tao T Huo Lei L Li Xi X Xia Xuefeng X Liu Zhixiong Z Wu Jun J
Scientific reports 20191105 1
Tremendous efforts have been made to explore biomarkers for classification and grading on gliomas. The goal of this study was to identify more molecular features that are associated with clinical outcomes by comparing the genomic profiles of primary and recurrent gliomas and determine potential recurrence leading factors that are significantly enriched in relapse tumors. Hybrid capture based next generation sequencing (NGS) analysis was performed on 64 primary and 17 recurrent glioma biopsies. C ...[more]