Reconstructing Foveola by Foveolar Internal Limiting Membrane Non-Peeling and Tissue Repositioning for Lamellar Hole-Related Epiretinal Proliferation.

ABSTRACT: Differences in the pathogenesis and clinical characteristics between lamellar macular hole (LMH) with and without LMH-associated epiretinal proliferation (LHEP) can have surgical implications. This study investigated the effects of treating LHEP by foveolar internal limiting membrane (ILM) non-peeling and epiretinal proliferative (EP) tissue repositioning on visual acuity and foveolar architecture. Consecutive patients with LHEP treated at our institution were enrolled. The eyes were divided into a conventional total ILM peeling group (group 1, n?=?11) and a foveolar ILM non-peeling group (group 2, n?=?22). In group 2, a doughnut-shaped ILM was peeled, leaving a 400-?m-diameter ILM without elevated margin over the foveola after EP tissue repositioning. The EP tissue was elevated, trimmed, and inverted into the LMH. Postoperatively, the LMH was sealed in all eyes in group 2, with significantly better best-corrected visual acuity (-0.26 vs -0.10 logMAR; p?=?0.002). A smaller retinal defect (p?=?0.003), a more restored ellipsoid zone (p?=?0.002), and a more smooth foveal depression (p?

SUBMITTER: Ho TC 

PROVIDER: S-EPMC6831694 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature