Unknown

Dataset Information

0

Low seroprevalence of hepatitis E on Reunion island.


ABSTRACT: Objective:Hepatitis E virus (HEV) has been scarcely investigated in the Indian Ocean. Following a nationwide serosurvey among blood donors, we conducted a population-based serosurvey to assess the magnitude of HEV exposure on Reunion Island. Methods:Four hundred and sixty-six archived frozen human sera from the 2009 CoPanFlu-RUN cohort were analysed using the Wantai HEV IgG enzyme immunoassay. HEV seropositivity was defined as an IgG titre ?5 UI/ml. Raw and weighted seroprevalences were assessed to account for the discrepancy between the CoPanFlu-RUN subset and the general community. Prevalence proportion ratios (PPR) were measured using log-binomial models. Results:The raw and the weighted seroprevalences of HEV were 9.01% (95% CI 6.41-11.61) and 6.73% (95% CI 4.47-8.98), respectively. The presence of HEV IgG antibodies was associated with increasing age (P?

SUBMITTER: Gerardin P 

PROVIDER: S-EPMC6831862 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications


<h4>Objective</h4>Hepatitis E virus (HEV) has been scarcely investigated in the Indian Ocean. Following a nationwide serosurvey among blood donors, we conducted a population-based serosurvey to assess the magnitude of HEV exposure on Reunion Island.<h4>Methods</h4>Four hundred and sixty-six archived frozen human sera from the 2009 CoPanFlu-RUN cohort were analysed using the Wantai HEV IgG enzyme immunoassay. HEV seropositivity was defined as an IgG titre ≥5 UI/ml. Raw and weighted seroprevalence  ...[more]

Similar Datasets

| S-EPMC6617902 | biostudies-literature
| S-EPMC7118902 | biostudies-literature
| S-EPMC6602885 | biostudies-literature
| S-EPMC3290959 | biostudies-literature
| S-EPMC4350561 | biostudies-literature
| S-EPMC4833340 | biostudies-literature
| S-EPMC2878351 | biostudies-literature
| S-EPMC3605158 | biostudies-literature
| S-EPMC10370861 | biostudies-literature
| S-EPMC8962908 | biostudies-literature