Dataset Information

In-vitro bioactivity evaluation and physical properties of an epoxy-based dental sealer reinforced with synthesized fluorine-substituted hydroxyapatite, hydroxyapatite and bioactive glass nanofillers.

ABSTRACT: The purpose of this study was to evaluate the physical properties and bioactivity potential of epoxy-based dental sealers modified with synthesized bioactive glass (BAG), hydroxyapatite (HA) and fluorine substituted hydroxyapatite (FHA) nanoparticles. The synthesized powders were incorporated at 10% and 20% into the epoxy-based dental sealer. The setting time, flow and solubility and microhardness of the modified and unmodified samples were examined. The bioactivity was evaluated using FESEM-EDX and elemental mapping, ATR-FTIR and XRD. The flow value of all of the experimental groups except the FHA modified samples, was greater than 20?mm. Concerning solubility, no specimens exhibited more than 1% weight loss. The solubility value of the FHA groups was statistically significant lower than other groups (p???0.001). The mean hardness values of all of the modified samples were significantly higher than the unmodified group (p???0.001). Regarding bioactivity, in vitro study revealed that after 3 days immersion in SBF a compact and continuous calcium phosphate layer formed on the surface of epoxy sealers containing BAG and HA nanoparticles. Based on these results, the addition of BAG and HA nanoparticles did not adversely alter the physical properties of epoxy sealers. Additionally, they improved the in vitro bioactivity of the epoxy sealer.

SUBMITTER: Jerri Al-Bakhsh BA

PROVIDER: S-EPMC6833307 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

<i>In-vitro</i> bioactivity evaluation and physical properties of an epoxy-based dental sealer reinforced with synthesized fluorine-substituted hydroxyapatite, hydroxyapatite and bioactive glass nanofillers.

Jerri Al-Bakhsh Bahaa Abdulrazzaq BA Shafiei Farhad F Hashemian Atieh A Shekofteh Kiana K Bolhari Behnam B Behroozibakhsh Marjan M

Bioactive materials 20191028

The purpose of this study was to evaluate the physical properties and bioactivity potential of epoxy-based dental sealers modified with synthesized bioactive glass (BAG), hydroxyapatite (HA) and fluorine substituted hydroxyapatite (FHA) nanoparticles. The synthesized powders were incorporated at 10% and 20% into the epoxy-based dental sealer. The setting time, flow and solubility and microhardness of the modified and unmodified samples were examined. The bioactivity was evaluated using FESEM-EDX ...[more]

PMID: 31709315

Similar Datasets

Project description:BackgroundThe regeneration of lost/damaged support tissue in the periodontium, including the alveolar bone, periodontal ligament, and cementum, is an ambitious purpose of periodontal regenerative therapy and might effectively reduce periodontitis-caused tooth loss. Guided tissue regeneration (GTR) is a technique currently used in dentistry for periodontal surgery, which allows osseous regeneration prior to soft tissue migration into the area of interest. Calcium phosphate-based bone grafts (mostly Tricalcium Phosphate or Hydroxyapatite) are bio ceramics that show the greatest similarity to the mineral found in the bone. Thereby, giving calcium-phosphate excellent biocompatibility, biodegradability and osteoconductivity. The aim of the study is to fabricate hydroxyapatite reinforced polymeric hydrogel membrane for regeneration.Materials and methodPure alginate fabrication was done by cross linking sodium alginate with calcium chloride. Hydroxyapatite (HAP) alginate (Alg) was formulated by adding nanoparticles to the alginate mixture, which was then cross-linked with calcium chloride to formulate a HAP alginate polymeric membrane. The Fourier-transform infrared spectroscopy (FT-IR), Scanning Electron Microscope (SEM), and biocompatibility tests were performed to analyse the membrane characteristics.ResultsFabricated Hydroxyapatite- alginate (Hap- Alg) membrane has longer durability, because of strong crystal structure which in turn might take a longer time to regenerate. The membrane was found to be biocompatible and HAp induces faster mineralisation which in turn will increase the tissue regeneration rate of the membrane.ConclusionThe findings of our study suggests that the HAP-Alg hydro gel membrane is highly durable and hemocompatible and it has faster mineralisation capability thus making it superior from the clinically available membranes for GTR. Further analyses needs to be conducted to evaluate the potential of this membrane to be used for regeneration.

Dataset Information

In-vitro bioactivity evaluation and physical properties of an epoxy-based dental sealer reinforced with synthesized fluorine-substituted hydroxyapatite, hydroxyapatite and bioactive glass nanofillers.

Publications

<i>In-vitro</i> bioactivity evaluation and physical properties of an epoxy-based dental sealer reinforced with synthesized fluorine-substituted hydroxyapatite, hydroxyapatite and bioactive glass nanofillers.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets