Ontology highlight
ABSTRACT:
SUBMITTER: Ge J
PROVIDER: S-EPMC6834916 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Ge Jinghua J Gargey Akhil A Nesmelova Irina V IV Nesmelov Yuri E YE
Journal of muscle research and cell motility 20190925 3-4
Calcium plays an essential role in muscle contraction, regulating actomyosin interaction by binding troponin of thin filaments. There are several buffers for calcium in muscle, and those buffers play a crucial role in the formation of the transient calcium wave in sarcomere upon muscle activation. One such calcium buffer in muscle is ATP. ATP is a fuel molecule, and the important role of MgATP in muscle is to bind myosin and supply energy for the power stroke. Myosin is not a specific ATPase, an ...[more]