The Association between Alcohol Consumption and Serum Metabolites and the Modifying Effect of Smoking.

ABSTRACT: Alcohol consumption is an important lifestyle factor that is associated with several health conditions and a behavioral link with smoking is well established. Metabolic alterations after alcohol consumption have yet to be comprehensively investigated. We studied the association of alcohol consumption with metabolite patterns (MPs) among 2433 individuals from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study, and a potential modification by smoking. Alcohol consumption was self-reported through dietary questionnaires and serum metabolites were measured by a targeted approach. The metabolites were summarized as MPs using the treelet transform analysis (TT). We fitted linear models with alcohol consumption continuously and in five categories. We stratified

SUBMITTER: Langenau J 

PROVIDER: S-EPMC6836136 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature