Dataset Information

Effects of parental genetic divergence on gene expression patterns in interspecific hybrids of Camellia.

ABSTRACT: BACKGROUND:The merging of two divergent genomes during hybridization can result in the remodeling of parental gene expression in hybrids. A molecular basis underling expression change in hybrid is regulatory divergence, which may change with the parental genetic divergence. However, there still no unanimous conclusion for this hypothesis. RESULTS:Three species of Camellia with a range of genetic divergence and their F1 hybrids were used to study the effect of parental genetic divergence on gene expression and regulatory patterns in hybrids by RNA-sequencing and allelic expression analysis. We found that though the proportion of differentially expressed genes (DEGs) between the hybrids and their parents did not increase, a greater proportion of DEGs would be non-additively (especially transgressively) expressed in the hybrids as genomes between the parents become more divergent. In addition, the proportion of genes with significant evidence of cis-regulatory divergence increased, whereas with trans-regulatory divergence decreased with parental genetic divergence. CONCLUSIONS:The discordance within hybrid would intensify as the parents become more divergent, manifesting as more DEGs would be non-additively expressed. Trans-regulatory divergence contributed more to the additively inherited genes than cis, however, its contribution to expression difference would be weakened as cis mutations accumulated over time; and this might be an important reason for that the more divergent the parents are, the greater proportion of DEGs would be non-additively expressed in hybrid.

SUBMITTER: Zhang M

PROVIDER: S-EPMC6842218 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Effects of parental genetic divergence on gene expression patterns in interspecific hybrids of Camellia.

Zhang Min M Tang Yi-Wei YW Qi Ji J Liu Xin-Kai XK Yan Dan-Feng DF Zhong Nai-Sheng NS Tao Nai-Qi NQ Gao Ji-Yin JY Wang Yu-Guo YG Song Zhi-Ping ZP Yang Ji J Zhang Wen-Ju WJ

BMC genomics 20191108 1

<h4>Background</h4>The merging of two divergent genomes during hybridization can result in the remodeling of parental gene expression in hybrids. A molecular basis underling expression change in hybrid is regulatory divergence, which may change with the parental genetic divergence. However, there still no unanimous conclusion for this hypothesis.<h4>Results</h4>Three species of Camellia with a range of genetic divergence and their F<sub>1</sub> hybrids were used to study the effect of parental g ...[more]

PMID: 31703692

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Dataset Information

Effects of parental genetic divergence on gene expression patterns in interspecific hybrids of Camellia.

Publications

Effects of parental genetic divergence on gene expression patterns in interspecific hybrids of Camellia.

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