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Target-Site Mutations Conferring Herbicide Resistance.


ABSTRACT: Mutations conferring evolved herbicide resistance in weeds are known in nine different herbicide sites of action. This review summarizes recently reported resistance-conferring mutations for each of these nine target sites. One emerging trend is an increase in reports of multiple mutations, including multiple amino acid changes at the glyphosate target site, as well as mutations involving two nucleotide changes at a single amino acid codon. Standard reference sequences are suggested for target sites for which standards do not already exist. We also discuss experimental approaches for investigating cross-resistance patterns and for investigating fitness costs of specific target-site mutations.

SUBMITTER: Murphy BP 

PROVIDER: S-EPMC6843678 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Target-Site Mutations Conferring Herbicide Resistance.

Murphy Brent P BP   Tranel Patrick J PJ  

Plants (Basel, Switzerland) 20190928 10


Mutations conferring evolved herbicide resistance in weeds are known in nine different herbicide sites of action. This review summarizes recently reported resistance-conferring mutations for each of these nine target sites. One emerging trend is an increase in reports of multiple mutations, including multiple amino acid changes at the glyphosate target site, as well as mutations involving two nucleotide changes at a single amino acid codon. Standard reference sequences are suggested for target s  ...[more]

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