Ontology highlight
ABSTRACT:
SUBMITTER: Heath EI
PROVIDER: S-EPMC6844084 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Heath Elisabeth I EI Heilbrun Lance K LK Smith Daryn D Schopperle William M WM Ju Yawen Y Bolton Susan S Ahmed Quratulain Q Sakr Wael A WA
Anticancer research 20181101 11
<h4>Background/aim</h4>Podocalyxin, a member of the CD34 family of cell surface sialomucins, is overexpressed in human embryonal carcinoma cell lines, as well as in several cancer types, and is associated with poor prognosis. Podocalyxin variants are associated with an increased risk and aggressiveness of prostate cancer. Herein podocalyxin protein expression in prostate cancer was characterized.<h4>Materials and methods</h4>Expression of podocalyxin as well as of TRA-1-60 and TRA-1-81 antigens ...[more]