Ontology highlight
ABSTRACT:
SUBMITTER: Tan P
PROVIDER: S-EPMC6844499 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Tan Puwen P Ren Yue Y Zhang Yuncong Y Lin Yunqing Y Cui Tianyu T Huang Yan Y Zhang Yang Y Ning Lin L Yu Jia J Gao Shuai S Wang Dong D Huang He H
Autophagy 20190830 11
Macroautophagy/autophagy has been demonstrated to play an essential role in embryonic development. However, the role of autophagy during human fetal digestive tract development has not been investigated. Here, by using over 5,000 human embryonic digestive tract cells ranging from 6 weeks to 25 weeks, we explored the dynamic expression of autophagy-related genes at single-cell resolution, and found that the transcriptional activity of autophagy-related genes boosted remarkably and specifically in ...[more]