Ontology highlight
ABSTRACT:
SUBMITTER: Ouahrani-Bettache S
PROVIDER: S-EPMC6844557 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Virulence 20191201 1
<i>Brucella microti</i> was isolated a decade ago from wildlife and soil in Europe. Compared to the classical <i>Brucella</i> species, it exhibits atypical virulence properties such as increased growth in human and murine macrophages and lethality in experimentally infected mice. A spontaneous rough (R) mutant strain, derived from the smooth reference strain CCM4915<sup>T</sup>, showed increased macrophage colonization and was non-lethal in murine infections. Whole-genome sequencing and construc ...[more]