Ontology highlight
ABSTRACT:
SUBMITTER: Liu P
PROVIDER: S-EPMC6848112 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Liu Peidang P Li Dan D Li Wenjie W Wang Dayong D
Scientific reports 20191111 1
Caenorhabditis elegans is useful for assessing biological effects of spaceflight and simulated microgravity. The molecular response of organisms to simulated microgravity is still largely unclear. Mitochondrial unfolded protein response (mt UPR) mediates a protective response against toxicity from environmental exposure in nematodes. Using HSP-6 and HSP-60 as markers of mt UPR, we observed a significant activation of mt UPR in simulated microgravity exposed nematodes. The increase in HSP-6 and H ...[more]