Ontology highlight
ABSTRACT:
SUBMITTER: de Farias TDSM
PROVIDER: S-EPMC6848267 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
de Farias Talita da Silva Mendes TDSM Cruz Maysa Mariana MM de Sa Roberta Cavalcante da Cunha RCDC Severi Ilenia I Perugini Jessica J Senzacqua Martina M Cerutti Suzete Maria SM Giordano Antonio A Cinti Saverio S Alonso-Vale Maria Isabel Cardoso MIC
Frontiers in endocrinology 20191105
Obesity results from critical periods of positive energy balance characterized by caloric intake greater than energy expenditure. This disbalance promotes adipose tissue dysfunction which is related to other comorbidities. Melatonin is a low-cost therapeutic agent and studies indicate that its use may improve obesity-related disorders. To evaluate if the melatonin is efficient in delaying or even blocking the damages caused by excessive ingestion of a high-fat diet (HFD) in mice, as well as impr ...[more]