Effectiveness of Shared Decision-making for Diabetes Prevention: 12-Month Results from the Prediabetes Informed Decision and Education (PRIDE) Trial.

ABSTRACT: IMPORTANCE:Intensive lifestyle change (e.g., the Diabetes Prevention Program) and metformin reduce type 2 diabetes risk among patients with prediabetes. However, real-world uptake remains low. Shared decision-making (SDM) may increase awareness and help patients select and follow through with informed options for diabetes prevention that are aligned with their preferences. OBJECTIVE:To test the effectiveness of a prediabetes SDM intervention. DESIGN:Cluster randomized controlled trial. SETTING:Twenty primary care clinics within a large regional health system. PARTICIPANTS:Overweight/obese adults with prediabetes (BMI???24 kg/m2 and HbA1c 5.7-6.4%) were enrolled from 10 SDM intervention clinics. Propensity score matching was used to identify control patients from 10 usual care clinics. INTERVENTION:Intervention clinic patients were invited to participate in a face-to-face SDM visit with a pharmacist who used a decision aid (DA) to describe prediabetes and four possible options for diabetes prevention: DPP, DPP ± metformin, metformin only, or usual care. MAIN OUTCOMES AND MEASURES:Primary endpoint was uptake of DPP (??9 sessions), metformin, or both strategies at 4 months. Secondary endpoint was weight change (lbs.) at 12 months. RESULTS:Uptake of DPP and/or metformin was higher among SDM participants (n =?351) than controls receiving usual care (n =?1028; 38% vs. 2%, p 

SUBMITTER: Moin T 

PROVIDER: S-EPMC6848409 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature