Medication Management Capacity and Its Neurocognitive Correlates in Huntington's Disease.
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ABSTRACT: Objective
Although medication management is a necessary daily activity for individuals with Huntington's disease (HD), medication management abilities and their relation to cognitive functioning have not been evaluated.Method
Twenty individuals with HD and 20 healthy adults (HA) completed the Medication Management Abilities Assessment (MMAA). Individuals with HD also completed a self-report medication management measure and neuropsychological tests assessing executive function, retrospective memory, and prospective memory.Results
Individuals with HD performed significantly poorer and made more undertaking errors on the MMAA as compared to HA. No group differences were found in overtaking errors. In the HD group, significant associations were found between undertaking errors and perceived medication management ability as well as between MMAA task performance and measures assessing prospective memory and executive functions.Conclusions
Medication management capacity was negatively affected in individuals with HD and may be associated with difficulty remembering to take medications in the future.
SUBMITTER: Sumida CA
PROVIDER: S-EPMC6849462 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
Medication Management Capacity and Its Neurocognitive Correlates in Huntington's Disease.
Sumida Catherine A CA Van Etten Emily J EJ Lopez Francesca V FV Sheppard David P DP Pirogovsky-Turk Eva E Corey-Bloom Jody J Filoteo J Vincent JV Woods Steven P SP Gilbert Paul E PE Schmitter-Edgecombe Maureen M
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 20191001 7
<h4>Objective</h4>Although medication management is a necessary daily activity for individuals with Huntington's disease (HD), medication management abilities and their relation to cognitive functioning have not been evaluated.<h4>Method</h4>Twenty individuals with HD and 20 healthy adults (HA) completed the Medication Management Abilities Assessment (MMAA). Individuals with HD also completed a self-report medication management measure and neuropsychological tests assessing executive function, r ...[more]
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