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Science-based Targets for Antibiotics in Receiving Waters from Pharmaceutical Manufacturing Operations.

ABSTRACT: In 2016, the United Nations declared the need for urgent action to combat the global threat of antimicrobial resistance (AMR). In support of this effort, the pharmaceutical industry has committed to measures aimed at improving the stewardship of antibiotics both within and outside the clinic. Notably, a group of companies collaborated to specifically address concerns related to antibiotic residues being discharged from manufacturing sites. In addition to developing a framework of minimum environmental expectations for antibiotic manufacturers, science-based receiving water targets were established for antibiotics discharged from manufacturing operations. This paper summarizes the holistic approach taken to derive these targets and includes previously unpublished, company-generated, environmental toxicity data.

SUBMITTER: Tell J

PROVIDER: S-EPMC6849714 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Science-based Targets for Antibiotics in Receiving Waters from Pharmaceutical Manufacturing Operations.

Tell Joan J Caldwell Daniel J DJ Häner Andreas A Hellstern Jutta J Hoeger Birgit B Journel Romain R Mastrocco Frank F Ryan Jim J JJ Snape Jason J Straub Jürg Oliver JO Vestel Jessica J

Integrated environmental assessment and management 20190501 3

In 2016, the United Nations declared the need for urgent action to combat the global threat of antimicrobial resistance (AMR). In support of this effort, the pharmaceutical industry has committed to measures aimed at improving the stewardship of antibiotics both within and outside the clinic. Notably, a group of companies collaborated to specifically address concerns related to antibiotic residues being discharged from manufacturing sites. In addition to developing a framework of minimum environ ...[more]

PMID: 30884149

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Dataset Information

Science-based Targets for Antibiotics in Receiving Waters from Pharmaceutical Manufacturing Operations.

Publications

Science-based Targets for Antibiotics in Receiving Waters from Pharmaceutical Manufacturing Operations.

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