Ontology highlight
ABSTRACT:
SUBMITTER: Kodaira H
PROVIDER: S-EPMC6850125 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Kodaira Himiko H Koma Yu-Ichiro YI Hosono Masayoshi M Higashino Nobuhide N Suemune Kazuki K Nishio Mari M Shigeoka Manabu M Yokozaki Hiroshi H
Pathology international 20190213 3
Tumor-associated macrophages (TAMs) have important roles in the growth, angiogenesis and progression of various tumors. Although we have demonstrated the association of an increased number of infiltrating CD204<sup>+</sup> TAMs with poor prognosis in esophageal squamous cell carcinomas (ESCCs), the roles of TAMs in ESCC remain unclear. Here, to study the effects of TAMs on the tumor microenvironment of ESCCs, we established a co-culture assay using a human ESCC cell line and TAM-like peripheral ...[more]