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Cost-effectiveness of interventions to reduce the risk of healthcare-acquired infections in middle-income countries: A systematic review.


ABSTRACT: Background:Hospital-acquired infections (HAI) contribute to prolonged hospital stays and account for a substantial economic burden to healthcare systems. Middle-income countries (MICs) experience a greater burden of HAI than developed countries. Evidence on the cost-effectiveness of interventions to reduce HAI is required to inform decision-making in these settings. Aim:To synthesise the evidence on cost-effectiveness as related to HAI interventions in MICs and to assess the quality of this evidence. Methods:A systematic review of published literature on the cost-effectiveness of interventions to reduce the incidence of HAI in MICs between 2000 and 2018 was conducted. Results:Six studies met the pre-determined inclusion criteria. The studies were from three countries: Thailand; India; and Vietnam. The evidence suggests that interventions to reduce HAI are cost-effective and, in most cases, cost-saving to healthcare systems. The quality of the reporting varied across studies. Conclusions:The implementation of HAI prevention interventions appears to be a high value use of resources in MICs. There is a need for further cost-effectiveness analyses in a wider range of MICs in order to confirm these findings. Improved standardisation and quality of reporting is required.

SUBMITTER: Gamalathge PU 

PROVIDER: S-EPMC6851621 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Cost-effectiveness of interventions to reduce the risk of healthcare-acquired infections in middle-income countries: A systematic review.

Gamalathge Pushpa Udayangani PU   Kularatna Sanjeewa S   Carter Hannah E HE   Senanayake Sameera S   Graves Nicholous N  

Journal of infection prevention 20190604 6


<h4>Background</h4>Hospital-acquired infections (HAI) contribute to prolonged hospital stays and account for a substantial economic burden to healthcare systems. Middle-income countries (MICs) experience a greater burden of HAI than developed countries. Evidence on the cost-effectiveness of interventions to reduce HAI is required to inform decision-making in these settings.<h4>Aim</h4>To synthesise the evidence on cost-effectiveness as related to HAI interventions in MICs and to assess the quali  ...[more]

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