Ontology highlight
ABSTRACT:
SUBMITTER: Giorgino F
PROVIDER: S-EPMC6852007 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Giorgino Francesco F Yu Maria M Haupt Axel A Milicevic Zvonko Z García-Pérez Luis-Emilio LE
Diabetes, obesity & metabolism 20190816 11
The long-acting glucagon-like peptide-1 receptor agonist dulaglutide acts by stimulating insulin secretion and reducing glucagon levels in a glucose-dependent manner both in the fasting and postprandial states, resulting in reductions of both fasting glucose (FG) and postprandial glucose (PPG). In contrast, the main mechanism of action of basal insulin is to reduce elevated FG by inhibiting hepatic glucose production. The aim of the present post hoc analysis of the phase 3 AWARD-2 trial was to i ...[more]